Comparative Evaluation of the Antimicrobial Efficacy of 50% Foeniculum vulgare mouthwash and 0.2% Chlorhexidine mouthwash on Streptococcus mutans : A Randomised Control Trial
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Dr Shubhashree Gandhe
- Enrollment
- 42
- Locations
- 1
- Primary Endpoint
- Antimicrobial Efficacy of 50% Foeniculum vulgare mouthwash against Streptococcus mutans
Overview
Brief Summary
| First year undergraduates will be | |
| selected as patient. |
Patient will be explained about the procedure and its outcome. Healthy patients will be selected and randomly divided into two groups as Group A and Group B using Computer generated Randomized sequence.
GROUP A : Patients administered with Foeniculum vulgare (Funnel seed) mouthwash .
GROUP B : Patient administered with Chlorhexidine mouthwash.
Double blinding will be conducted that is both the participant and the clinical evaluator will be blinded .
| A third party |
| keeps the allocation key (which mouthwash corresponds to which code). |
Unblinding occurs only after data collection and statistical analysis — or earlier only if adverse events require it. Salivary sample of 2 mL will be collected in a sterile plastic bottle
The samples will be tested for the microbiological analysis for the colony-forming units (CFU) of S. mutans.
Patient of both the group will be advised to rinse their mouth for 1 minute using 5 mL of the mouthwash daily. The second sample will be taken only after 21 days after using mouthwashes and counted for colonies.
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- Participant and Outcome Assessor Blinded
Eligibility Criteria
- Ages
- 17.00 Year(s) to 25.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •First-year undergraduate dental students.
- •Systemically healthy individuals.
Exclusion Criteria
- •History of current or past 1-month antibiotic usage.
- •Cellulitis, abscess, draining sinus, or other emergency dental treatment.
Outcomes
Primary Outcomes
Antimicrobial Efficacy of 50% Foeniculum vulgare mouthwash against Streptococcus mutans
Time Frame: 21 days
Secondary Outcomes
- To check the antimicrobial efficacy of herbal mouthwash over allopathic mouthwash(21 days)
Investigators
Dr Shubhashree Gandhe
SMBT IDSR