Comparative Evaluation of the Antimicrobial Efficacy of 50% Foeniculum vulgare mouthwash and 0.2% Chlorhexidine mouthwash on Streptococcus mutans : A Randomised Control Trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Antimicrobial Efficacy of 50% Foeniculum vulgare mouthwash against Streptococcus mutans
研究概览
简要总结
| First year undergraduates will be | |
| selected as patient. |
Patient will be explained about the procedure and its outcome. Healthy patients will be selected and randomly divided into two groups as Group A and Group B using Computer generated Randomized sequence.
GROUP A : Patients administered with Foeniculum vulgare (Funnel seed) mouthwash .
GROUP B : Patient administered with Chlorhexidine mouthwash.
Double blinding will be conducted that is both the participant and the clinical evaluator will be blinded .
| A third party |
| keeps the allocation key (which mouthwash corresponds to which code). |
Unblinding occurs only after data collection and statistical analysis — or earlier only if adverse events require it. Salivary sample of 2 mL will be collected in a sterile plastic bottle
The samples will be tested for the microbiological analysis for the colony-forming units (CFU) of S. mutans.
Patient of both the group will be advised to rinse their mouth for 1 minute using 5 mL of the mouthwash daily. The second sample will be taken only after 21 days after using mouthwashes and counted for colonies.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 17.00 Year(s) 至 25.00 Year(s)(—)
- 性别
- All
入选标准
- •First-year undergraduate dental students.
- •Systemically healthy individuals.
排除标准
- •History of current or past 1-month antibiotic usage.
- •Cellulitis, abscess, draining sinus, or other emergency dental treatment.
结局指标
主要结局
Antimicrobial Efficacy of 50% Foeniculum vulgare mouthwash against Streptococcus mutans
时间窗: 21 days
次要结局
- To check the antimicrobial efficacy of herbal mouthwash over allopathic mouthwash(21 days)
研究者
Dr Shubhashree Gandhe
SMBT IDSR
