Comparative Evaluation of post operative sore throat after nebulization with magnesium sulphate versus lidocaine in patients undergoing general anaesthesia.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 52
- 试验地点
- 1
研究概览
简要总结
This is a Prospective, double-blind, Randomized Control Trial to compare the incidence of post operative sore throat after nebulization with magnesium sulphate versus lidocaine in patients undergoing general anaesthesia requiring endotracheal intubation, to assess effect of nebulisation with magnesium sulphate and lidocaine on haemodynamic parameters, post operative sedation overall patient comfort post-surgery and any drug related side effects.
Incidence of sore-throat in both groups will be observed at 0, 2, 4, 6, 12, 24 hours post-surgery.Haemodynamic parameters - HR, SBP, DBP, MAP and SpO2 will be observed just prior to administering nebulisation, at the time of induction of GA and at the time of extubation
Post operative sedation will be assessed as per Ramsay sedation score
Any postoperative side effect or complications will be noted
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •1- American Society of Anaesthesiology (ASA) grade I and II 2- Hemodynamically stable patients with all routine investigations within the normal limits.
- •3- Patients who give informed written consent and are willing to be a part of the study.
排除标准
- •Patient refusal to be a part of the study
- •History of allergy to the drug being used in the study
- •Patients with severe cardiovascular or respiratory disorders
- •Patients on steroid therapy
- •Subjects who cough or bucked before extubation 7.
研究者
Niveditha Kishore Srinivasan
Department of Anaesthesiology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune