Treatment of schizophrenia with venlafaxine
- Conditions
- Schizophrenia.Schizophrenia
- Registration Number
- IRCT2012101011076N1
- Lead Sponsor
- Kurdistan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion criteria
(1)-DSM-IV diagnosis for shizophrenia.
(2)-Age between 18-59 years old.
(3)-Not presenting of moderate to severe depression according to the beck depression inventory.
(4)-Total PANSS Sc ore>60.
(5)- Present of significant negative symptoms (PANSS negative sub score>20).
(6)-Patient medication dose does not change during past 3 month of study.
(7)-Patient's medications must be risperidone or olanzapin.
(8)-Obtaining the written informed consent.
Exclusion criteria:
(1)-Additional diagnosis in axis 1 according to DSM-IV.
(2)-Substance abuse or dependence except nicotine.
(3)-Pregnant women.
(4)-Women in fertility ages which does not use OCP.
(5)-History of allergic reaction to venlafaxine.
(6)-Giving ECT during previous 2 months.
(7)- On methadone maintenance therapy.
(8)-Patients with increased intra ocular pressure or in the risk of close angle glaucoma.
(9)-Hepatic cirrhosis.
(10)-Breast feeding women.
(11)-Cimetidine consumption in the presence of HTN or hepatic impairment.
(12)-Another psychotropic drugs consumption except benzodiazepins.
(13)-Mental Retardation.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method