Effects of combination therapy with sitagliptin and metformin on glycemic control-related factor, beta-cell function, lipid profile, and kidney function in patients with type 2 diabetes.
Not Applicable
- Conditions
- Type 2 diabetes
- Registration Number
- JPRN-UMIN000013509
- Lead Sponsor
- Misaki naika clinic
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1) type 1 diabetes 2) had ketosis or coma within 6 month 3) after severe infection, operation or injure 4) impaired renal function (Serum Cr>1.5mg/dL for male,>1.3mg/dL for female) 5) is pregnancy or chance of pregnant 6) Under treatment by other anti-diabetic drugs 7) Has allergy to DPP-4 inhibitor 8) Patient who was considered to be appropriate to this study by attending physician
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change rate of HbA1c
- Secondary Outcome Measures
Name Time Method Chage rate of fasting blood glucose, active GLP-1, proinsulin / insulin ratio (P / I), HOMA-beta, HOMA-R, general lipid, RLP-C, LPL, HPLC lipoprotein quantitative analysis (H) , urinary albumin (ACR), cystatin C, L-type fatty acid binding protein (L-FABP), liver function.