A Clinical study to evaluate effectiveness of Shuddha Gandhaka Prayoga in Vicharchika

Phase 3

Not yet recruiting

• Conditions: Atopic dermatitis, unspecified,

• Registration Number: CTRI/2023/10/058990
• Lead Sponsor: Dr Soumya Sajjanar

Brief Summary

Title:A CLINICAL STUDY TOEVALUATE THE CONCEPT OF VYADHI PRATYANIKA CHIKITSA WITH SPECIAL REFERENCE TOKSHEERA GANDHAKA PRAYOGA IN VICHARCHIKA

**Purpose:** To validate the concept of Vyadhipratyanikachikitsa in Vicharchika using Ksheera Gandhaka for period of 15 days. Gandhaka ismentioned as drug of choice in Rasendra Chintamani and Caraka Mentions GandhakaPrayoga for all types of Kushta; it possesses qualities like Kushtahara,Kandughna, Visrpahara, Vishahara, Rasayana guna etc. by the virtue of *Katu Tikta Rasa, Ushnaveerya*and it will act against *Vicharchika.* KsheeraGandhaka is a simple yoga for administration and easily available and costeffective. There are less works dedicated towards Gandhaka Prayoga and anupanaas Ksheera, hence a thorough work on its action and efficacy is required.

**Methods:** Vicharchika is classified into two groups basedon the lakshana (Sravi and Asravi) and 20 subjects in each group. Both thegroups will be given 6-12g of Triphala Churna condsidering the koshta ofsubjects for Ksohta Shuddhi. Later both the groups will be given at the dose of1g. Shuddha Gandhaka(Shodhana as per Rasaratna Samucchaya) and Ksheera asAnupana and Ksheeranna Bhojana as Pathya. Assessments will be carried out on 0th,8th day. Follow up on the 15th day. Standard proformaswill be used for assessment and follow up.

**Results:** Results will be tabulated and statistically treated by Wilcoxon SignRank Test and Friedm’s test, Whitney U Test and Paired T Test.

**Conclusion:** The study will helpunderstand Vyadhipratyanika Chikitsa Concept in Vicharhika and provides awindow to understand how Shuddha Gandhaka Works with Ksheera as anupana.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-05-10
• Study Start: 2023-10-21

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Chronicity less than 2 years Localized lesion to certain area will be selected.
• Diagnosed cases of sravi and asravi vicharhika Willingness to participate in the study and ready to sign informed consent form.

Exclusion Criteria

Pregnant and Lactating Women Subjects on steroids/immunosuppressants Allergy to sulphur Subjects with systemic disorders or chronic disorders.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
intervention will be effective in reduction of lesion size, discharge from lesion, pain at lesion site, itching.	after 7 days

Secondary Outcome Measures

Name	Time	Method
Evaluation of Ayurveda Concept of Vyadhi Prtyanika Chikitsa will be done.	effectiveness of Shuddha Gandhaka as Vyadhi Pratyanika in Vicharchika lakshanas such as itching, lesion size, discharge, pain at lesion site will be noted.

Trial Locations

Locations (1)

SRI DHARMASTHALA MANJUNATHESHWARA COLLEGE OF AYURVEDA AND HOSPITAL HASSAN; 🇮🇳 Hassan, KARNATAKA, India

SRI DHARMASTHALA MANJUNATHESHWARA COLLEGE OF AYURVEDA AND HOSPITAL HASSAN

🇮🇳Hassan, KARNATAKA, India

Dr soumya sajjanar

Principal investigator

9663365234

soumyasajjanar.7s@gmail.com