Evaluation of Quality of Life and Its Influencing Factors After VA-ECMO in Refractory Cardiac Arrest Based on SF-36 Score : A Grenoble Cohort Study From 2006 Through 2018

Completed

• Conditions: Refractory Cardiac Arrest; ExtraCorporeal Membrane Oxygenation (ECMO)
• Interventions: Other: SF36 questionnaire via telephone interview

• Registration Number: NCT04601896
• Lead Sponsor: University Hospital, Grenoble

Brief Summary

If the ExtraCorporeal Membrane Oxygenation (ECMO) improves survival in the management of refractory cardiac arrest (RCA), this technique is still an invasive technique, not devoid of complications and requiring intensive care that can have serious consequences for patients. If the studies so far show an acceptable quality of life post ECMO in refractory cardiac arrest, the study looks about the quality of life of our patients in Grenoble who survived a refractory cardiac arrest between 2006 and 2018 at the hospital university Grenoble Alps and the factors influencing this quality of life.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-10-13
• Study Start: 2020-10-16
• Study First Submitted QC: 2020-10-20
• Study First Posted: 2020-10-26
• Status Verified: 2020-12
• Primary Completion: 2021-01-15
• Study Completion: 2021-04-27
• Last Update Submitted: 2021-04-27
• Last Update Posted: 2021-04-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• Adult >18 years
• Admission to intensive care unit after a Refractory Cardiac Arrest
• Hemodynamic instability after resumption of spontaneous cardiac activity.
• Non-opposition of the patient or his relatives
• Admission to intensive care unit From 2006 Through 2018

Exclusion Criteria

• ECMO for hypothermia or drug intoxication.
• Comorbidity contraindicated the ECMO
• Patients dead before hospital discharge

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Live patients quality of life admitted for Refractory Cardiac Arrest without ECMO	SF36 questionnaire via telephone interview	-
Live patients admitted for Refractory Cardiac Arrest with ECMO	SF36 questionnaire via telephone interview	-

Primary Outcome Measures

Name	Time	Method
Global quality of life score	Through study completion, an average of 3 months	Items from the SF36 (Short Form 36) survey

Secondary Outcome Measures

Name	Time	Method
Vital status	Through study completion, an average of 3 months	Deed/Lived
Live patients characteristics description	Through study completion, an average of 3 months	Demographic and clinical retrospective data collection
Quality of life score related at live patients characteristics description	Through study completion, an average of 3 months	Items from the SF36 (Short Form 36) survey matched with live patients characteristics description
Quality of life score comparison	Through study completion, an average of 3 months	Items from the SF36 (Short Form 36) survey compared between the 2 groups ( RCA with /without ECMO) admitted from january 2015 and december 2018

Trial Locations

Locations (1)

Chu Grenoble Alpes; 🇫🇷 Grenoble, France