Effects of Beef Protein Consumption on Energy Intake - The Protein Leverage Hypothesis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obesity
- Sponsor
- Maastricht University Medical Center
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Body weight change
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this study is to determine ad libitum daily energy intake, body weight changes and appetite profile in response to protein/carbohydrate and fat ratio over 12 consecutive days, and in relation to age, gender, body mass index (BMI) and fat mass and obesity-associated (FTO) gene alleles.
Detailed Description
The protein leverage hypothesis requires specific evidence whether energy intake would depend on a possible protein intake target in humans. Meat protein as complete protein may show most beneficial effects on variables regarding food intake regulation.
Investigators
Eveline Martens
PhD student
Maastricht University Medical Center
Eligibility Criteria
Inclusion Criteria
- •Age 18-70 years
- •BMI 18-35 kg/m2
- •Non-smoking
- •Weight stable
Exclusion Criteria
- •Use of medication
- •More than moderate alcohol consumption
- •Vegetarian
Outcomes
Primary Outcomes
Body weight change
Time Frame: 11 days
Body weight will be measured on day 1, 6 and 12. Subsequently, the change in body weight over time will be calculated.
Appetite profile
Time Frame: 12 consecutive days
Appetite profile will be measured by means of questionnaires: visual analogue scales (VAS). Area under the curve (AUC) will be calculated over 12 consecutive days.
Energy intake
Time Frame: 12 consecutive days
Total energy intake over 12 days will be determined for each subject by adding energy intake during meals to energy intake from snack consumption.