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Clinical Trials/ISRCTN12980412
ISRCTN12980412
Completed
Not Applicable

A prospective randomised controlled trial assessing the efficacy of intravitreal bevacizumab in patients with minimally classic and occult choroidal neovascularisation secondary to age-related macular degeneration

Frimley Park Hospital NHS Trust (UK)0 sites100 target enrollmentDecember 18, 2007
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ConditionsAge-related macular degenerationEye Diseases

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Age-related macular degeneration
Sponsor
Frimley Park Hospital NHS Trust (UK)
Enrollment
100
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
December 18, 2007
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Frimley Park Hospital NHS Trust (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. Age \>50 years
  • •2\. Fluorescein angiographic evidence of minimally classic or occult choroidal neovascular membrane
  • •3\. Best Corrected Visual Acuity (BCVA) 20/40 \- 20/320
  • •4\. BCVA in no study eye better than 20/320
  • •5\. If both eyes are eligible then only the worst eye will be enrolled
  • •6\. Willing to attend scheduled visits

Exclusion Criteria

  • •1\. Medical conditions:
  • •1\.1\. Uncontrolled hypertension
  • •1\.2\. Patients on more than 3 antihypertensive medications
  • •1\.3\. Patients in whom a change in anti\-hypertensive drug was initiated within 3 months preceding baseline visit.
  • •1\.4\. Previous thrombembolic phenomenon
  • •1\.5\. On Warfarin or anticoagulants
  • •1\.6\. Recent Myocardial Infarction (MI)
  • •1\.7\. Recent major surgery (within 28 days)
  • •2\. Ocular conditions:
  • •3\. Glaucoma (IntraOcular Pressure \[IOP] \>25, on anti\-glaucoma treatment, glaucoma surgery)

Outcomes

Primary Outcomes

Not specified

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