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临床试验/NCT01054157
NCT01054157Unknown不适用

Expression and Localization of FP Prostaglandin Receptor in Human Ocular Tissues

Meir Medical Center0 个研究点目标入组 50 人开始时间: 2010年2月最近更新:
适应症

试验速览

阶段
不适用
入组人数
50

研究概览

简要总结

to approve the expression of PGF2α receptors in hair follicle in ocular skin tissue, explaining the hypertrichotic effect of PG analogues as intraocular pressure lowering treatment.

详细描述

50 hair follicle dissection - human lower lid skin and lashes will be derived from lateral tarsal strip (LTS) dissected routinely in ectropion repair surgery, the skin strip is dissected routinely in this surgery , without any relation to our study. The study will be planned according to Helsinki declaration for Paraffin embedded LTS tissue sections (4 µ) will be processed and examined in immunohistochemistry lab. FP receptor proteins expression, using subtype-specific polyclonal antibodies, will be detected by the light microscopic level, according to manufacturer instruction.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age > 18 years
  • malposition of lower eyelid

排除标准

  • age < 18 years

研究者

申办方类型
Other

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