Impact of galacto-oligosaccharides on microbial fermentation capacity and markers of frailty in adults and elderly

Completed

• Conditions: Gastrointestinal symptoms; 10017943

• Registration Number: NL-OMON45484
• Lead Sponsor: niversiteit Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

No gastrointestinal complaints
Age between 25-50 years (and robust by citeria of Fried et al. 2001) and 70-85 years (and prefrail by criteria of Fried et al. 2001)
BMI between 20 and 30 kg/m2

Exclusion Criteria

Use of antibiotics in the 90 days prior to the study
Use of laxatives within 14 days prior to the study
Pregnancy
Administration of probiotic or prebiotic supplements in the 14 days prior to the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Microbial composition and activity</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Innate immune signaling and defence<br /><br>Metabolite production<br /><br>Digestive parameters / side effects</p><br>