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Thickness of Breathing Muscle before surgery in liver donor and recipient scheduled for liver transplant :A compariso

Not Applicable
Completed
Conditions
Health Condition 1: null- LIVER TRANSPLANT DONOR AND RECIPIENT
Registration Number
CTRI/2017/05/008631
Lead Sponsor
Institute of Liver and Biliary Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Inclusion criteria

Recipient

1. Patients with CLD of any etiology

2. 18-70 years

3. BMI >18 <30

4.MELD Score >=15 and undergoing living donor liver transplantation

Donor

1.Healthy ASA I or II eligible donors

2.BMI >18 <30

Exclusion Criteria

Exclusion criteria

Recipient

1. Age less than 18 years and more than 70 years

2.Acute liver failure

3.Repeat transplant

4.Previous history of COPD, Asthma

5.BMI <18 or >30

6.Previous major thoracic or abdominal surgery

7.Subgroup analysis- Re-intubation due to repeat surgery because of any cause, poor graft function/PGNF

Donor

1.BMI <18 or >30

2.Previous major thoracic or abdominal surgery

3.Previous history of COPD, Asthma

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To find preoperative thickness of diaphragm in chronic liver disease recipients scheduled for Living donor liver transplantation.Timepoint: Only at one time just before giving anaesthesia to patients in operation theatre
Secondary Outcome Measures
NameTimeMethod
â?¢To find if recipients with reduced diaphragmatic thickness have higher postoperative weaning failure and prolonged hospital stay.Timepoint: Till the patient will be off <br/ ><br> from ventilatory support, extubated and discharged from intensive care units/ Wards
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