Clinical Study on Management of Kaphaja Kasa with drug Madhvasava:An open labelled Clinical trial.

Phase 2/3

Not yet recruiting

• Conditions: Diseases of the respiratory system. Ayurveda Condition: KASAH,

• Registration Number: CTRI/2025/03/083090
• Lead Sponsor: Goverment Akhandanand Ayurveda College, Ahmedabad

Brief Summary

In the pathogenesis of disease Kaphaj Kasa, vitiated Kapha obstructs the free flow of Vayu in Kantha and Uras. Since Kapha is the main culprit in the production of Kasa      indulgence in food and activities which aggravate Kapha increases the severity of Kaphaj Kasa. Exposure cold environment, sleeping in daytime usually aggravates Kaphaj Kasa. Thus Vata and Kapha are the two key pathological factors involved in the Samprapti of Kaphaj Kasa. Kaphaj Kasa is the clinical entity in which there is coating of cough in mouth, Kapha sampoorna ura (feeling of phlegm collected in the chest), aversion to food, feeling of heaviness of the body, debility, cough followed by thick sputum.



Madhvasava having Chedi, Tikshna, Kaphaghna and kasahara effects, thus eliminating episodic recurrence of kaphaja kasa and provide a cure from disease to the patient.

Diagnostic Criteria

Kanthoplepa

Asya madhurya

Pinasa

Vaksh sampurnaiv manyate

Ghana – snigdha – sweta – bahul shleshm pravarthanam

Aruchi

Excess quantity of Sputum

Present study is being planned to evaluate the study on Kaphaja kasa with drug Madhvasava. The sample size is 40 patients. Madhvasava will be given in 15 ml dose in muhur muhur dose (6-8 times / day).

Study duration is of 7 days and follow up after 7 days.

Study Design is Open Labelled Clinical Trial.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-04-15
• Last Update Posted: 2025-11-03

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Patients willing to participate and give written informed consent.
• Patients in the age group of 18-70 years of either sex.
• Patients with signs and symptoms of Kaphaj Kasa.

Exclusion Criteria

• Patients below 18 yrs & above 70 yrs.
• Patients having Pneumonia, Pulmonary Tuberculosis, Pneumothorax, Pleural effusion, Bronchial Asthma, COPD, Bronchiectasis, etc.
• Any congenital anomalies related to respiratory or cardiovascular systems.
• The patient suffering from malignant systemic disorders.
• Patients having Uncontrolled HTN, Poorly controlled Diabetes mellitus, Unstable Angina, Coronary artery disease.
• Red Flag Signs associated with Cough: Hemoptysis, Breathlessness, Weight Loss, Fever.
• Patients having severe Renal or any Hepatic disease.
• Pregnant or lactating females.
• Acute and serious conditions which require emergency intervention will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in the symptoms of kaphaja kasa	7 days

Secondary Outcome Measures

Name	Time	Method
Improvement in the symptoms of kaphaja kasa	Day 7

Trial Locations

Locations (1)

Goverment Akhandanand Ayurveda College; 🇮🇳 Ahmadabad, GUJARAT, India

Goverment Akhandanand Ayurveda College

🇮🇳Ahmadabad, GUJARAT, India

Nihal Kanziya

Principal investigator

9426939410

nihalkanziya12@gmail.com