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临床试验/NL-OMON37958
NL-OMON37958已完成不适用

Effects of temporary discontinuation of antihypertensive treatment in older patients with cognitive impairment: a randomised controlled trial. The DANTE Study Leiden, Discontinuation of ANtihypertensive Treatment in the Elderly - DANTE study Leiden.

eids Universitair Medisch Centrum0 个研究点目标入组 400 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
400

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • (1) age >= 75 years,
  • (2) current antihypertensive treatment with a calcium antagonist, beta-blocker, diuretic, ACE-inhibitor, or angiotensin-II-receptor blocker prescribed by their general practitioner for hypertension,
  • (3) a last systolic blood pressure as reported in the chart of the general practitioner <= 160 mmHg(4) Mini-Mental State Examination (MMSE) score 21t/m 27.

排除标准

  • A history of myocardial infarction and/or coronary reperfusion procedures (CABG/PCI) < 3 years, stroke, or heart failure requiring antihypertensive medication and/or a clinical diagnosis of dementia.

研究者

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