Is cows’ first milk an acceptable and effective way of improving gut health and nutrition in children with Crohn’s disease?

Not Applicable

Completed

• Conditions: Crohn's disease in children; Digestive System

• Registration Number: ISRCTN78570360
• Lead Sponsor: Alder Hey Children's NHS Foundation Trust

Brief Summary

2022 Results article in https://doi.org/10.3390/nu14214598 (added 02/12/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-07-08
• Study Completion: 2021-07-26
• Last Update Posted: 9 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

1. Aged 8 years and above
2. CD in clinical remission or mild/moderate disease severity (weighted pCD Activity Index [wPCDAI] =57.5)
3. Stable clinical condition defined as either receiving no treatment or maintenance therapy that has been unchanged for at least the last 2 months with no intention to change therapy at the time of recruitment
4. Willing for clinical information to be used for the purposes of the trial
5. Willing to partake in the study procedures
6. Able to complete the daily diary in English

Exclusion Criteria

1. Severe CD (wPCDAI >57.5)
2. Intolerance of dairy products
3. Receiving dietary therapy for the management of Crohn’s disease (e.g. Modulen IBD)
4. Already taking BC regularly
5. Established diagnosis of a significant gut disorder other than CD (e.g. short bowel syndrome)
6. Failure to obtain informed consent from the patient and/or parent/guardian

Study & Design

• Study Type: Interventional
• Study Design: Not specified