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临床试验/EUCTR2014-005640-18-DK
EUCTR2014-005640-18-DK进行中(未招募)1 期

Does perineural clonidin prolong the duration of an adductor canal block when controlling for a systemic effect? - a randomized, blinded, paired study in healthy volunteers.

Køge Sygehus0 个研究点目标入组 21 人开始时间: 2015年1月8日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
21

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
Male

入选标准

  • BMI >18 and < 30
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range 21
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range 21

排除标准

  • Allergy to study medication
  • Alkoholconsumption > 21 unit sof alcohol per week
  • Medical abuse (judged by the investigator)
  • Daily intake of perscription painkillers within 4 weeks
  • Intake of over the counter medication within 48 hours
  • Earlier trauma og surgery to lower limb
  • Diabetes mellitus
  • Heart block 2. og 3. degree
  • Sick sinus node
  • Failed blocks will be excluded from the paired analysis (no sensory change and therefore zero duration) but partial blocks (Defined as loss of cold sensation (alcohol swab) and pin-prick at t=2h but VAS > 0 during tonic heat stimulation test at t=2h) will be included in ITT but not PPA.

研究者

发起方
Køge Sygehus

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