Prognostic Value of Cardiac Output Measured by Impedancemetry in Patients Monitored for Pulmonary Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 59
- 试验地点
- 2
- 主要终点
- Measure of cardiac flow variation at 6 month by impedancemetry
研究概览
简要总结
Monocentric cohort study, prospective, evaluating the variability of cardiac output measurement by resting and stress impedancemetry as a prognostic factor for Pulmonary Hypertension
详细描述
Cardiac impedancemetry is a technique that allows an electrical representation of cardiac flows. To do this, 6 electrodes are applied to the thorax and a low intensity and high frequency electrical current is transmitted. The impedance is recorded and the variations of the impedance represent the changes in intra-thoracic volume and thus the volume of systolic ejection. This measurement can be done at rest but also during exercise during the walking test. A test of the NO / CO coupled transfer measurement is also performed.
The devices that will be used in this project are the Physio-Flow® system and Masterscreen NO / CO coupled transfer measurement device
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient over 18 years and under 80 years
- •Patients who have been diagnosed with PAH (group 1 PH according to the Nice 2013 classification) or post-embolic pulmonary hypertension (group 4 PH) under medical treatment;
- •HTP incident or prevalent less than 6 months
- •Patient coming for follow-up or emergency consultation or hospitalization with a clinical examination and a walking test
- •Patient affiliated to a health insurance scheme
- •Patient having signed informed consent
排除标准
- •Subjects under juridical protections or tutelage measure
- •pregnant or lactating woman
- •pulmonary hypertension du to cardiac pathology, chronic respiratory disease, or uncertain determinism.
- •pulmonary hypertension of group 4 treated surgically or endoscopically.
- •pulmonary hypertension incident or prevail for 6 months or more
- •contraindication to impedancemetry
- •inability to perform a walking test
结局指标
主要结局
Measure of cardiac flow variation at 6 month by impedancemetry
时间窗: 6 month
The variation of cardiac flow is measured by impedancemetry at rest
Measure of cardiac flow variation at 0 month by impedancemetry
时间窗: 0 month
The variation of cardiac flow is measured by impedancemetry at rest
次要结局
- Measure of cardiac flow variation during walking test at 6 month(6 month)
- Correlation between measurement of capillary blood volume and measurement of cardiac flow(6 month)
- Occurrence of an undesirable event(18 month)
- Measure of cardiac flow variation during walking test(0 month)