Social Behavior in Depression

• Conditions: Depression

• Registration Number: NCT03414606
• Lead Sponsor: Beijing Normal University

Brief Summary

In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-02-01
• Study First Submitted: 2018-01-22
• Study First Submitted QC: 2018-01-26
• Study First Posted: 2018-01-30
• Status Verified: 2018-02
• Last Update Submitted: 2018-02-04
• Last Update Posted: 2018-02-06
• Primary Completion: 2018-02-16
• Study Completion: 2018-03-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• Age range between 18 and 60
• Education experience above high school
• Score for Hamilton's Depression Scale >=17
• Diagnosis of depression through Scid

Exclusion Criteria

• Undergoing electric shock treatment in 3 months
• Excluding those who with bipolar disorder
• Excluding those who with postpartum depression
• Excluding those who with hysteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Valuation of social information	Baseline	The valuation of social information was measured by psychological paradigm, developed from animal studies, called "pay-per-view". The participants will be asked make decision about more social information or more monetary reward.
Emotion recognition	Baseline	After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.
Cognitive flexibility	Baseline	Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.
Optimism bias	Baseline	Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.
Prosocial behavior	Baseline	The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.
Model-free & model-based tendency	Baseline	Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.

Trial Locations

Locations (1)

Huilongguan Hospital; 🇨🇳 Beijing, China