NL-OMON36912CompletedPhase 3
Prevention of radiation-induced parotid gland dysfunction by parotid-gland stem-cell sparing intensity-modulated radiotherapy (SCS-IMRT) - Parotid gland stem cell sparing radiotherapy
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Completed
- Enrollment
- 102
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •Patients treated with planned curative primary radiotherapy for HNC, with or without chemotherapy or cetuximab meeting the following criteria:
- •- Squamous cell carcinoma originating from the mucosa of the head and neck area or nasofaryngeal carcinoma originating from the nasofarynx;
- •- The radiotherapy includes prophylactic or therapeutic irradiation of both sides of the neck (at least level II to IV);
- •- Age * 18 years;
- •- WHO performance 0-2;
- •- pre-treatment stimulated parotid gland saliva production >0.2 ml/min.
Exclusion Criteria
- •- Postoperative radiotherapy;
- •- Re-irradiation;
- •- Unilateral radiotherapy;
- •- Primary salivary gland tumours
Investigators
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