Clinical Cohort Study to Evaluate Survival Rate of Endodontically Treated Premolars Versus Implant Placement:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 130
- 主要终点
- Periapical index (PAI) for retreatment
研究概览
简要总结
Introduction: To evaluate the survival and success rate of premolars with a previous root canal treatment which underwent to non-surgical retreatment or to extraction and implant replacement.
Materials and methods: Patients visiting in the Clinical Endodontic Section of the School of Dentistry (University of Bologna) were eligible for the study. Out of these patients, those with previously root canal treated premolars fulfilled the inclusion criteria. Teeth were considered retreatable and restorable (Endo group) or not retreatable and not restorable (Implant group) on the basis of clinical and radiographical examination. Each patient was included in an annual recall programme and final evaluation was performed after 8 years. Clinical parameters were recorded. Differences in baseline characteristics between the two treatment groups were assessed using logistic regression analysis with clustered standard errors. Results were expressed for each variable as odds ratios (ORs) of implant rehabilitation to root canal retreatment with 95% confidence intervals (CIs). Survival and treatment success for the two study groups were estimated using the Kaplan-Meier method. The association of treatment group with time to event was assessed using Cox proportional hazard regression analysis with clustered standard errors to allow for intragroup correlation within teeth belonging to the same patient. Results were expressed as hazard ratios (HRs) of experiencing the study event among implants as compared to root canal retreatments with 95% CIs.
详细描述
This historical cohort study evaluated the survival and success rate of first and second premolars with a previous root canal treatment which underwent secondary root canal treatment vs. extraction and implant replacement.
The study was planned as a historical cohort of patients followed for 8 years. This work was written according to Consolidated Standards of Reporting trials guidelines for reporting clinical trials, and was conducted in full accordance with ethical principles, including the Declaration of Helsinki. At the time of treatment, an informed consent was signed by each participant.
Patients treated at our university department from January 2007 to December 2015 were eligible to be included in the study.
The final evaluation was performed between January 2019 and March 2023 in the University Department.
The primary consideration for inclusion in the study was that both approaches had a sound clinical and biological rationale and were acceptable in terms of cost for the patient. Nevertheless, the final decision was always made by a pool of operators based on their experience and adherence to evidence-based dentistry and best clinical practices.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Periapical index (PAI) for retreatment
时间窗: preoperative, 4 year, 8 years
PAI 1-2 = no lesions PAI 3-5= periapical lesions
Marginal bone levels (MBL) for implant insertion
时间窗: during insertion for the implant placement procedure, at 4 years, at 8 years
MBL measured on periapical radiographs
次要结局
- Survival(4 years 8 years)
研究者
Fausto Zamparini
University of Bologna
University of Bologna
