Ultrasound-based Breast Cancer Screening in Chinese Women
试验速览
- 阶段
- 不适用
- 入组人数
- 20,000
- 试验地点
- 16
- 主要终点
- number of cancer detected in the high-risk group
研究概览
简要总结
In the present study, the investigators will screen breast cancer of the Chinese women based on ultrasound and aim to compare the risk evaluation model of PUMCH model which was established by our previous work with other risk models.
详细描述
Early detection of breast cancer through screening has been a common practice in the United States and several European countries for decades. It is effective in reducing the mortality of breast cancer and improving the postoperative quality of life of patients. Mammography has been the standard imaging method for the screening, however, our previous study has shown that ultrasound is more sensitive and less expensive than mammography. In the present study, the investigators will screen breast cancer of the Chinese women based on ultrasound and aim to evaluate the risk model (PUMCH model) which was established by our previous work.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 75 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Written informed consent；
- •residence from community or working units
排除标准
- •pregnancy；
- •lactation；
- •known metastatic cancer；
- •signs or symptoms of breast disease；
- •presence of breast implants, breast surgery within prior 12 months；
- •had mammography or ultrasound exam within prior 12 months
结局指标
主要结局
number of cancer detected in the high-risk group
时间窗: 3 years
次要结局
未报告次要终点
研究者
Qiang SUN
Director
Peking Union Medical College Hospital