EUCTR2005-004632-40-BE
Active, Not Recruiting
N/A
Study on the pharmacodynamic interactions between propofol and sevoflurane during induction of anesthesia.
niversity Hospital Ghent0 sites60 target enrollmentFebruary 8, 2006
ConditionsAnesthesia
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Anesthesia
- Sponsor
- niversity Hospital Ghent
- Enrollment
- 60
- Status
- Active, Not Recruiting
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •American Society of Anesthesia class I and II patients
- •18\-60 years
- •Scheduled for surgery under general anesthesia
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) no
- •F.1\.3\.1 Number of subjects for this age range
Exclusion Criteria
- •Weight less than 70% or more than 130% of ideal body weight
- •neurological disorder
- •diseases involving the cardiovascular system (hypertension, coronary artery disease, prior AMI, any valvular and/or muscular disease involving decrease of the ejection fraction, arrhythmias, which are either symptomatic or require continuous medication/pacemaker/AICD)
- •pulmonary disease including asthma, severe COPD, ...
- •Gastric diseases including reflux
- •Endocrinological diseases
- •recent use of psycho\-active medication, including alcohol
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Phase 1
Evaluation of pharmacokinetic interactions between the antidiabetic metformin andthe antibiotic trimethoprim.E11.90DRKS00000481niversität Heidelberg, Medizinische Fakultät24
Completed
N/A
Evaluation of Pharmacokinetic interaction between vitamin K1 and ezetimibeHealthy volunteerJPRN-UMIN000002327Department of Hospital Pharmacy, Hamamatsu University School of Medicine10
Completed
N/A
The pharmacokinetic study of drug interaction between metformin and pyrimethamine from microdose to clinical dose in adult healthy volunteershealthy male subjectsJPRN-UMIN000002739Clinical trial Center,Kitasato University East Hospital8
Completed
N/A
Confirming the pharmacological interaction between colchicine and 18F-choline PETProstate cancer10038597NL-OMON38465Antoni van Leeuwenhoek Ziekenhuis5
Completed
Phase 1
Pharmacokinetic drug-drug interaction study between oral 300 mg netupitant/0.50 mg palonosetron fixed dose combination (Akynzeo®) and oral dexamethasone to evaluate the duration of the CYP3A4 inhibition in healthy subjectsInhibitory effect on CYP3A4Not ApplicableISRCTN93845260Helsinn Healthcare SA24