PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes in Obese Women
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- schrimer test
研究概览
简要总结
Women with polycystic ovarian syndrome (PCOS) may complain dryness of their eyes especially obese ones. lifestye changes are main treatrment fro both problems
详细描述
Forty females with PCOS, eye dryness , and obesity will asigned to group I or Group II, n=20 for each group. Both groups will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •PCOS women
- •obese class I
- •bilateral dryness of eye
排除标准
- •liver disoease
- •cardiac disease
- •renal disease
研究组 & 干预措施
group number 1
twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks.
干预措施: exercise and limiting diet (Behavioral)
group number 2
Twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks.
干预措施: diet limitation (Behavioral)
结局指标
主要结局
schrimer test
时间窗: it will be measured after 12 weeks
it is a test for assessment dye dryness
次要结局
- Ocular surface disability index(It will be measured after 12 weeks)
- dry eye scoring system(It will be measured after 12 weeks)
- Tear film break-up time(It will be measured after 12 weeks)
- body mass index(it will be measured after 12 weeks)
- wasit hip ratio(It will be measured after 12 weeks)
- wasit circumference(It will be measured after 12 weeks)
- testesterone(It will be measured after 12 weeks)
- LH:FSH ratio(It will be measured after 12 weeks)
- dehydroepiandrosterone(It will be measured after 12 weeks)
研究者
Ali Mohamed Ali ismail
lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Cairo University