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临床试验/NCT02842606
NCT02842606已完成不适用

Effects of the Consumption of Fiber-enriched Pasta on Glucose and Lipid Metabolism and Satiety

Federico II University0 个研究点目标入组 13 人开始时间: 2015年3月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
13
主要终点
Glucose and lipid response

研究概览

简要总结

Cardio-metabolic diseases are a leading cause of mortality worldwide. Over the years, therefore, there have been considerable efforts to identify strategies for prevention and management of risk factors. The diet, with its pleiotropic effects, is one of the most effective approaches to reduce the cardio-metabolic risk. In this context, the dietary fibers have been extensively studied and the available evidence supports the beneficial effects of its consumption. However, worldwide the average fiber consumption is still less than the recommended daily dose. For this reason, the availability of functional foods, such as additional sources of fiber in the diet, may facilitate the attainment of fiber recommended.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
30 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • BMI 18-29 kg / m2
  • Good Health status

排除标准

  • Cardiovascular events (IMA or stroke) severe heart disease
  • Kidney or liver failure
  • Anemia and any other chronic disease

研究组 & 干预措施

Fiber-enriched pasta

Experimental

The participants consume whole wheat pasta with added fiber (fiber 12 g fiber/100 g).

干预措施: Test meal (Other)

Control pasta

Active Comparator

The participants consume pasta made from durum wheat semolina (fiber 2.7g/100g).

干预措施: Test meal (Other)

结局指标

主要结局

Glucose and lipid response

时间窗: 4 hours

Evaluated by enzymatic colorimetric methods

次要结局

  • Energy intake in the subsequent meal.(4 hours)
  • Insulin response(4 hours)
  • Hormone response (GLP-1, GIP, PYY and Ghrelin)(4 hours)

研究者

发起方
Federico II University
申办方类型
Other
责任方
Principal Investigator
主要研究者

rivellese angela

Full professor

Federico II University

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