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Clinical Trials/NCT05863624
NCT05863624
Not yet recruiting
Not Applicable

Postoperative Pain and Recurrences After Totally Extraperitoneal Endoscopic (TEP) vs. Lichtenstein Hernioplasty in Female Inguinal Hernia Repair: a Prospective Randomized Multi-center Study

Kuopio University Hospital1 site in 1 country170 target enrollmentSeptember 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Post Operative Pain
Sponsor
Kuopio University Hospital
Enrollment
170
Locations
1
Primary Endpoint
Chronic pain
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

This randomized study compares open inguinal hernia repair (Lichtenstein hernioplasty) to endoscopic repair (TEP) in terms of chronic pain and recurrences in one and five years after operation.

Detailed Description

The best operative technique in female inguinal hernia is not known. Some register studies recommend always laparoscopic hernia repair in females, but there are no randomized studies to show that laparoscopic repair is better than open hernioplasty. Our study compares operative complications, chronic pain and recurrences in Lichtenstein operation to totally endoscopic hernia repair (TEP) in 170 female patients with primary inguinal hernia. The patients are operated in six Finnish hospitals, randomized into 85 Lichtenstein vs 85 TEP and followed 1 week, 4 weeks, 12 months and 5 years. Main end-point in postoperative pain after one year, sencondary endpoints are sick leave, return to normal physical activity, complications of treatment, re-operations, chronic pain and costs of treatment.

Registry
clinicaltrials.gov
Start Date
September 1, 2024
End Date
December 31, 2029
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Kuopio University Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • primary inguinal hernia in females

Exclusion Criteria

  • emergency operation
  • recurrent hernia
  • groin pain without hernia
  • frail and sick patient ASA ≥ 4

Outcomes

Primary Outcomes

Chronic pain

Time Frame: from 1 week to one year

Postoperative inguinal pain (vas scores 0-10) after 1 week, 4 weeks and one year of surgery

Secondary Outcomes

  • Sick leave(0-30 days)
  • Recurrence(5 years)
  • Treatment costs(0-30 days)
  • Complications(1 month)

Study Sites (1)

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