Factors affecting insulin dose requirements for treatment of prednisolone induced hyperglycaemia.

Not Applicable

Completed

• Conditions: Prednisolone induced hyperglycaemia; Insulin resistance; Metabolic and Endocrine - Diabetes; Metabolic and Endocrine - Other metabolic disorders

• Registration Number: ACTRN12618001211257
• Lead Sponsor: Flinders Medical Centre

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-07-19
• Study Completion: 2021-08-30
• Last Update Posted: 27 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

1. Age greater than or equal to 18 years
2. Prescribed a morning dose of oral prednisolone greater than or equal to 20 mg/day for an acute inflammatory illness.
3. Hyperglycaemia in the prior 24 hours, defined as:
A) One point-of-care blood glucose greater than or equal to 15 mmol/L.
B) Two point-of-care blood glucose greater than or equal to 10 mmol/L.

Exclusion Criteria

1. by mouth or reduced oral intake.
2. Type 1 diabetes mellitus (T1DM).
3. Prescribed long-term oral prednisolone greater than or equal to 10 mg/day (or equivalent).
4. Psychiatric illness or another condition precluding providing informed consent.
5. Pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified