NCT01277120终止不适用
The Correlation Between the Moment of Bevacizumab theRapy initiatiOn and the Efficacy in patieNt With cOlorectal Cancer Treated With AvaStin Based First Line Regimens (CRONOS 1)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 174
- 主要终点
- Correlation of the time from the start of chemotherapy to the start of Avastin treatment with progression-free survival
研究概览
简要总结
This single arm, prospective, observational study will assess the correlation between the time from start of chemotherapy to the start of Avastin (bevacizumab) treatment with progression-free survival in patients with previously untreated metastatic colorectal cancer. Patients will be followed for up to 12 months after progressive disease occurs.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients, >/= the 18 years of age
- •Previously untreated metastatic colorectal cancer
- •Scheduled to start 1st line chemotherapeutic treatment
- •ECOG performance status 0-1
排除标准
- •Any conditions included in contraindication list for Avastin
- •Prior chemotherapy for metastatic colorectal cancer
- •Adjuvant/neoadjuvant chemotherapy or radio-chemotherapy of non-metastatic colorectal cancer completed <6 months prior to treatment start
结局指标
主要结局
Correlation of the time from the start of chemotherapy to the start of Avastin treatment with progression-free survival
时间窗: 60 months
次要结局
- Safety: Incidence of adverse events(60 months)
- Overall survival(60 months)
研究者
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