Taste Supra-thresholds Among a Sample of Depressed Egyptian Adult Under Anti-depressants Therapy

Completed

• Conditions: Taste Disorders

• Registration Number: NCT04923321
• Lead Sponsor: Cairo University

Brief Summary

Determine the taste intensity at supra-threshold among a sample of depressed Egyptian adults (age from 20 to 50 years old) under anti-depressants therapy ( for at least 3 months) using filter paper disc(FPD) method using a psychophysical method through a scoring system.

Detailed Description

PECO

* P Population: depressed Egyptian adults under anti-depressants therapy

* E1 Exposure 1: Tricyclic antidepressants (Imipramine, Amitriptyline, Clomipramine HCL)

* E2 Exposure 2: Selective Serotonin Re-uptake inhibitors antidepressants ( Fluoxetine, Fluvoxamine, Sertraline, Citalopram, Paroxetine)

* C control (non exposure) : non-pharmacological treatment ( psychotherapy)

* O Outcome: Determine the taste intensity at supra-threshold among these patients using a psychophysical method through a scoring system

Study Timeline

• Study Start: 2021-02-22
• Primary Completion: 2021-04-08
• Study Completion: 2021-05-07
• Study First Submitted: 2021-06-06
• Study First Submitted QC: 2021-06-06
• Study First Posted: 2021-06-11
• Status Verified: 2022-02
• Last Update Submitted: 2022-02-02
• Last Update Posted: 2022-02-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Depressed Egyptian adults under antidepressants therapy for at least 3 months/non-pharmacological treatment( psychotherapy) • Age from 20 to 50 years old

Exclusion Criteria

• Antipsychotics

  • Hypnotics
  • Anticonvulsants
  • Ages other than the mentioned • Olfactory dysfunction
  • Chemosensory dysfunction

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Taste intensity at supra-threshold	during a period of 3 months from February 2021 till April 2021]	- C.M will assess the taste intensity at supra-threshold level on a 9 point vertical labeled scale (extremely strong, very strong, strong, slightly strong, neutral, slightly weak, weak , very weak, extremely weak) in which subjects indicate the intensity perceived when tasting a substance

Trial Locations

Locations (1)

Faculty of Dentistry, Cairo University; 🇪🇬 Cairo, Egypt