Effect of Curcumin on Migraine
- Conditions
- Migraine.G43
- Registration Number
- IRCT20121216011763N34
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 44
Aged 20-50 years
Diagnose of migraine by neurologist
willing to participate on study
Lack of severe depression and anxiety and stress
Not taking Vitamin and Antioxidant supplements (Vitamin E and C ? Selenium ? Zinc and Beta carotene)
Not having tension headaches
Not taking Anti migraine drugs
The absence of severe chronic disease such as Cancer ? Hepatitis ? pancreatitis ? diabetes ? Thyroid disorders ? Kidney and Liver disease
Having no inflammatory diseases or history of heart disease and stroke and taking anti-inflammatory drugs
Unwilling to participate in the study
Use of antioxidant supplements, vitamins and anti-migraine drugs
Chronic diseases and tension headaches
Indication of allergic symptoms due to curcumin supplementation
Pregnancy and lactation, or any major change in lifestyle or diet
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of migraine, migraine frequency and duration of headache. Timepoint: The beginning and the end of the study. Method of measurement: Questionnaire.
- Secondary Outcome Measures
Name Time Method evels of IL-6, CGRP and TAC. Timepoint: The beginning and the end of the study. Method of measurement: Laboratory method.