Connectivity of a network associated with rest and inhibition of responses under the influence of atomoxetine/placebo in patients with attention-deficits/hyperactivity disorder-a pharmacological fMRTI study including a scan measuring brain activity while participants are in a resting state and while performing an inhibitory control task
- Conditions
- Patients with Attention-Deficit/Hyperactivity Disorders (ADHD)Therapeutic area: Psychiatry and Psychology [F] - Mental Disorders [F03]
- Registration Number
- EUCTR2013-002386-18-DE
- Lead Sponsor
- RWTH Aachen Clinical Trials Center Aachen (CTC-A)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Male
- Target Recruitment
- 52
Male
Age 18-45 years
Diagnosis of ADHD (patients) or no axis I disorder (controls) according the DSM IV
No substance abuse/ dependency
Understanding of the study information and declaration of agreement
Ability to read, understand and speak German
No severe medical disorders
No risk for suicide
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 52
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Drug dependence or the a positive drug screening
Other Severe physical disorders
Current pharmacological therapy because of another psychiatric disorder
Risk for seizure or cardiac problems
Impaired liver and renal function
Significant deviations in regard to clinical chemistry, haematology or EKG
Relationship of dependency with the sponsor or the investigator
Unable to keep to the study protocol
Known Intolerance of the study medication
fMRI scanner incompatibility
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method