Importance of IgE antibody fraction size on allergen sensitivity of basophils from cat allergic patients on Xolair. A pilot study.

S.G.O. Johansson, MD PhD Professor0 个研究点开始时间: 2006年7月5日最近更新: 2015年8月4日

适应症

试验速览

暂无简介。

•1.a clinical history of allergic asthma and/or rhinitis
•2.IgE –antibodies to cat
•3.total serum IgE level between 30 and 700 kU/L
•4.percent IgE antibodies to cat < 0.7% (Low group) or > 5.5% (High group)
•5.body weights: 40-150 kg
•6.adult outpatients of both sexes
•7.fulfil the general criteria, e.g health, non-pregnancy, for receiving Xolair for treatment of allergic asthma
•8. written informed consent.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•1.not subject to previous or ongoing ASIT with cat dander allergen.
•2.previously randomized into this or any other omalizumab study or who have received omalizumab by prescription.
•3. with known hypersensitivity to any ingredients, including excipients (sucrose, histidine, polysorbate 20) of the study medication or drugs related to omalizumab (e.g.: monoclonal antibodies, polyclonal gamma globulin).
•4.not be on treatment with oral corticosteroids or be judged to need such treatment during the trial.

发起方

S.G.O. Johansson, MD PhD Professor