Driving Time and Left-Cheek Skin Hydration Asymmetry in Florida Residents: An Observational Study on Cumulative UVA Exposure Through Vehicle Side Windows
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Hydration Asymmetry Index (HAI)
研究概览
简要总结
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida. In left-hand-drive vehicles, the driver's left cheek is chronically exposed to ultraviolet A (UVA) radiation through the unshaded side window during every daytime driving episode. A prior study by IAS Skin Care (NCT07564869, n=30) found that the left cheek was less hydrated than the right cheek in 60% of participants, suggesting a possible effect of driving-related UVA exposure on facial skin hydration asymmetry.
Eighty female drivers aged 25-65 years residing in Florida will be enrolled. At a single visit, skin hydration will be measured at three facial zones (left cheek, right cheek, and forehead as a symmetrical control zone) using the BT-Analyze bioimpedance device. Participants will complete a structured questionnaire on driving habits, sun protection practices, and skin history. The primary outcome is the Hydration Asymmetry Index (HAI = right cheek minus left cheek BT-Analyze score). Associations between driving time, cumulative driving exposure, window tinting, sunscreen use, and HAI will be examined using Spearman correlation, Mann-Whitney U tests, and multiple linear regression.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 25 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female sex, aged 25 to 65 years (inclusive)
- •Valid driver's license and active driving for a minimum of 3 years
- •Driving frequency of at least 3 days per week on average
- •Florida residency for a minimum of 2 years prior to enrollment
- •Ability to provide written informed consent in English or Russian
排除标准
- •Window tinting on the driver-side window of the participant's primary vehicle
- •Regular sunscreen application specifically to the left side of the face before driving (more than half of driving occasions in the past month)
- •Active skin disease on the face at time of assessment
- •Injectable cosmetic procedures (Botox or fillers) in the past 6 months
- •Laser resurfacing or chemical peel in the past 3 months
- •Inability to refrain from facial cosmetics for at least 2 hours prior to the visit
研究组 & 干预措施
Female Florida Drivers
Female drivers aged 25-65 years residing in Florida for at least two years, driving at least 3 days per week, without window tinting on the driver-side window.
干预措施: BT-Analyze bioimpedance skin hydration measurement (Other)
结局指标
主要结局
Hydration Asymmetry Index (HAI)
时间窗: Single visit (Day 1)
Difference in mean BT-Analyze bioimpedance scores between the right and left cheeks (HAI = right cheek mean minus left cheek mean). A positive value indicates lower hydration on the left cheek relative to the right.
次要结局
- Correlation between cumulative driving exposure and HAI(Single visit (Day 1))
- HAI by window tinting status(Single visit (Day 1))
- HAI by sunscreen application habit(Single visit (Day 1))
- Forehead hydration as symmetry reference(Single visit (Day 1))
研究者
Olga Ias
Licensed Esthetician, M.Sc.
IAS Skin Care