Evaluation of outcomes of radiotherapy in metastatic spinal cord compression in lung cancer
Completed
- Conditions
- metastatic spinal cord compression in lung cancer
- Registration Number
- CTRI/2016/06/006981
- Lead Sponsor
- Tata Memorial Centre
- Brief Summary
a prospective observational study to evaluatethe outcomes of radiotherapy in patient of lung cancer with metastatic spinalcord compression in terms of painrelief, improvement in motor function, sphincter control and overall survivalat 6 months
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- •Age 18 years and above •NSCLC/SCLC •Presence of solitary or multiple tumour deposits/soft tissue mass/metastatic disruption of the bony cortex around the spinal cord that are extrinsically compressing the thecal sac as diagnosed on MRI or CT or evidence of clinical myeloradiculopathy with or without osteolysis evident on X-Ray and or Bone Scan in patients with progressive neoplastic disease.
- •Informed consent (although have requested for waiver of consent from IEC).
Exclusion Criteria
•Surgical intervention for treatment of MSCC •Previous irradiation in the affected region of the spine.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective of this study is to evaluate the various radiotherapy regimen 2 weeks, 1 month and 6 months after completion of RT, with respect to : NIL •Sphincter control NIL •Pain Relief NIL •Improvement in motor function/Ambulatory status NIL
- Secondary Outcome Measures
Name Time Method To determine whether there is any difference in outcome with respect to overall survival. NA
Trial Locations
- Locations (1)
TATA MEMORIAL CENTRE, DEPARTMENT OF RADIATION ONCOLOGY
🇮🇳Mumbai, MAHARASHTRA, India
TATA MEMORIAL CENTRE, DEPARTMENT OF RADIATION ONCOLOGY🇮🇳Mumbai, MAHARASHTRA, IndiaDR JAI PRAKASH AGARWALPrincipal investigator02224177164agarwaljp@tmc.gov.in