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Clinical Trials/NCT03274830
NCT03274830
Active, Not Recruiting
N/A

A Post Market Clinical Follow-up Study With the aneXys Cup

Mathys Ltd Bettlach3 sites in 1 country102 target enrollmentMarch 5, 2020

Overview

Phase
N/A
Intervention
aneXys
Conditions
Arthroplasty, Replacement, Hip
Sponsor
Mathys Ltd Bettlach
Enrollment
102
Locations
3
Primary Endpoint
Cup migration after 2 years
Status
Active, Not Recruiting
Last Updated
2 months ago

Overview

Brief Summary

The purpose of the study is the evaluation of the clinical and radiological short- to long-term safety and performance of the aneXys cup. The data will be used for an ongoing evaluation of the product safety and performance.

Detailed Description

Prospective observational multicenter case series providing short-term migration results and long-term post-market clinical data on the safety and performance of the aneXys cup. The study includes patients undergoing primary total hip arthroplasty. In total 100 patients in 3 clinics will be included. In each clinic 10-57 consecutive patients shall be included. In addition, to meet the regulatory requirements, a total of minimum 20 cases with screw fixation shall be included in the study. Clinical and radiological follow-up (FU) is planned after 6-12 weeks, 6 months, 1, 2, 5, 7 and 10 years. An additional FU at 3 years is planned to apply for an ODEP (Orthopaedic Data Evaluation Panel) rating.

Registry
clinicaltrials.gov
Start Date
March 5, 2020
End Date
March 1, 2032
Last Updated
2 months ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Mathys Ltd Bettlach
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Informed consent form (signed by participant and investigator)
  • Primary implantation
  • Suffer from primary or secondary osteoarthritis of the hip, femoral head and neck fractures or necrosis of the femoral head. In all cases a stable anchoring of the implant has to be possible.
  • Age at inclusion: between 18 and 75 years old
  • Willing to participate in the follow-up examinations
  • Complete recovery is expected

Exclusion Criteria

  • Missing informed consent form (signed by participant and investigator)
  • Known or suspected non-compliance (e.g. drug or alcohol abuse)
  • Enrolment of the investigator, his/her family, employees and other dependent persons
  • Patients younger 18 years old
  • Revision surgery
  • Presence of sepsis or malignant tumours
  • ASA (American Society of Anesthesiologists) Classification \>3
  • Pregnancy

Arms & Interventions

aneXys

cases with aneXys cup and Mathys hip stem

Intervention: aneXys

Outcomes

Primary Outcomes

Cup migration after 2 years

Time Frame: 2 years

The primary endpoint will be the radiographic evaluation of the acetabular cup migration based on performed EBRA measurements 2 years after surgery.

Secondary Outcomes

  • Visual analogue scale vor pain(10 years)
  • The Western Ontario and McMaster Universities Osteoarthritis Index(10 years)
  • Harris Hip Score(10 years)
  • Visual analogue scale for satisfaction(10 years)

Study Sites (3)

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