A randomised comparative study on the effect of concomitant administration of various doses of intravenous phenylephrine with oxytocin for prevention of oxytocin-induced hypotension following caesarian section under spinal anesthesia.
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 78
- 试验地点
- 1
- 主要终点
- To study the effect of concomitant administration of various doses of phenylephrine with oxytocin for prevention of oxytocin-induced hypotension following caesarian section under spinal anesthesia
研究概览
简要总结
It is a prospective , comparative , randomised ,double blinded study to compare the effects od coadministration of oxytocin with two doses of phenylephrine 75mcgs 100mcgs and NS respectively in patients divided into three groups and haemodynamic balance is observed mainly the incidence of oxytocin induced hypotension during cesarean section under spinal anaesthesia .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- Female
入选标准
- •American Society of Anesthesiology (ASA) grade I and II,Singleton full term pregnant patients posted for caesarean section, Hemodynamically stable patients with all routine investigations within the normal limits and without any other co morbidities,Patients who give informed written consent and are willing to be a part of the study.
排除标准
- •unwilling female patients female patients above ASA3 female patient with any contraindication for neuraxial blockade.
结局指标
主要结局
To study the effect of concomitant administration of various doses of phenylephrine with oxytocin for prevention of oxytocin-induced hypotension following caesarian section under spinal anesthesia
时间窗: baseline vitals | every two minutes for first 10 minutes later every ten minutes till 70 minutes of procedure.
次要结局
- To evaluate Rescue vasopressor requirement(To observe the magnitude of hemodynamic changes)
研究者
Brinda Badam
DR D.Y. PATIL MEDICAL COLLEGE,HOSPITAL AND RESEARCH CENTRE