A randomized double-blind placebo controlled trial on the effect of magnesium oxide in patients with chronic constipatio
Not Applicable
- Conditions
- Chronic constipation diadnosed by Rome IV criteria
- Registration Number
- JPRN-UMIN000028973
- Lead Sponsor
- Hyogo College of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 34
Inclusion Criteria
Not provided
Exclusion Criteria
Candidates are excluded if they prescribe drug for constipation in hospital or use the over the counter medicines for constipation Everyday Candidates are excluded if they cannot use the over the counter medicines for constipation until fourteen days from consent of this study Candidates are excluded if any of the following are evident: current evidence of renal dysfuncti or cardiac disturbance or hypermagnesemia Secondary constipation candidates are excluded Candidates are excluded if take a madecine of the proton pump inhibitor or the potassium-competitive acid blocher Female patient could not be pregnant,as confirmed by a negative serum pregnancy test at the baseline visit
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method overall treatment efficacy
- Secondary Outcome Measures
Name Time Method 1.Monthly responder rates and weekly change from baseline in complete spontaneous bowel movement 2.Monthly responder rates and weekly change from baseline in spontaneous bowel movement 3.colon transit time 4.Bristol stool form 5.The patient assessment of constipation quality of life (JPAC-QOL) and SF-8 6.Weekly change from baselaine in symptom score of bloating 7.Weekly change from baselaine in symptom score of abdominal discomfort 8.Weekly change from baselaine in symptom score of afeeling of remaining faces 9.Weekly change from baselaine in symptom score of severity of straining