Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Ischemic Optic Neuropathy
- Sponsor
- Medical University of Bialystok
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- sigma parameter
- Last Updated
- 4 years ago
Overview
Brief Summary
The aim of the project is to create a new, non-invasive and safe protocol for the early diagnosis of various types of optic neuropathies with the use of diffusion magnetic resonance imaging
Detailed Description
In this study, it is planned to find twenty volunteers for each of the neuropathies and twenty healthy volunteers. Each volunteer will undergo clinical tests such as visual acuity, color vision, intraocular pressure measurement, assessment of the anterior chamber and fundus using a slit lamp and Volk lens, macular optical coherence tomography examination and examination of the optic nerve disc (OCT), neurological field vision and visual evoked potential (VEP) testing. Each of the volunteers will undergo magnetic resonance imaging. During active scanning, patients will be asked for not blinking or moving their heads by staring at the red dot on the outside of the camera reflected in the coil mirror. The obtained diffusion tensor data will be used for further analysis.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Optic neuropathy.
Exclusion Criteria
- •common contraindications to MRI (presence of pacemaker, non-MRI-safety or claustrophobia)
Outcomes
Primary Outcomes
sigma parameter
Time Frame: one month
sigma parameter in our algorithm provides a quantitative measure of nerve atrophy