NL-OMON42442
Recruiting
Not Applicable
The role of the immune system in Q Fever Fatigue Syndrome - QFS - Immunopathology
Stichting Q-support (verlenen subsidie)0 sites80 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coxiella burnetii
- Sponsor
- Stichting Q-support (verlenen subsidie)
- Enrollment
- 80
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Q Fever Fatigue Syndrome (QFS):
- •Diagnosis of QFS according to national LCI\-guideline Q fever fatigue syndrome (QFS)
- •Score \>\=40 on the subschale fatigue of the Checklist Individual Strength (CIS)
- •Severe functional impairment on Sickness Impact Profile\-8 (SIP\-8\), defined as a SIP total score \>\=700
- •Age \>\=18;Chronic Fatigue Syndrome (CFS):
- •Diagnosed with CFS according to CDC\-criteria (www.cdc.gov/cfs)
- •Score \>\=40 on the subschale fatigue of the CIS
- •Severe functional impairment on Sickness Impact Profile\-8 (SIP\-8\), defined as a SIP total score \>\=700
- •Age \>\=18;Cleared acute Q fever without residual symptoms:
- •Cleared acute Q fever (without residual symptoms)
Exclusion Criteria
- •Q Fever Fatigue Syndrome (QFS):
- •Use of immunosuppressant drugs during an acute Q fever infection or in the past 3 months
- •Use of antibiotics that are potentially active against C. Burnetii for at least 4 weeks, after the diagnosis acute Q fever was made;Chronic Fatigue Syndrome (CFS):
- •Use of immunosuppressant drugs in the past 3 months
- •History of Q fever
- •Chronic Q fever patients, according to the Dutch consensus \*Chronic Q fever\*
- •Vaccinated for Q fever
- •Pregnancy;Cleared acute Q fever without residual symptoms:
- •Use of immunosuppressant drugs during an acute Q fever infection or in the past 3 months
- •Chronic Q fever patients, according to the national consensus \*Chronic Q fever\* \[RIVM, Q\-koortsvermoeidheidssyndroom]
Outcomes
Primary Outcomes
Not specified
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