Effects of soy milk consumption on liver enzymes,lipid profile,glycemic status, markers of inflammation and oxidative stress and hepatic steatosis in non-alcoholic fatty liver patients.

Vice Chancellor for Research, Iran University of Medical Sciences0 个研究点目标入组 70 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

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•Inclusion criteria : patient aged 18- 60 y ; diagnosis of NAFLD in accordance to American Gastroenterological Association guidelines as follows: a) hepatic steatosis confirmed by ultrasonography , b) there are no cause for secondary steatosis such as alcohol consumption, hereditary disorders( e.g. hemochromatosis,wilson’s disease) ,autoimmune diseaseses ,hepatotoxic drugs (e.g. methotrexate , amiodaron, tamoxifen, corticosteroids, valproate and anti-viral drugs) and chronic hepatitis C ; Absence of any other co-disorders including but not limited to other chronic liver diseases (hepatitis), cirrhosis, celiac, diabetes, thyroid disorders, breast cysts, as well as cardiovascular, renal, respiratory ,inflammatory and autoimmune diseases ; Absence of cancer or a history of cancer in patient and his/her first-degree relatives ; BMI of 25 to 40 (kg/m2) ; having no allergy to soy milk ; consuming no nutritional supplements during the last two months ; Taking no anti-inflammatory drugs; hasn’t any history of drug abuse and smoking; no pregnancy or lactation ; willingness to participate and sign an informed written consent.
•Exclusion criteria: Lack of willingness to be a study participants during the study ; allergy or intolerance to soy milk during the study ; Lack of adherence to soy milk consumption ; existence of medical conditions that require special treatments during the study .

发起方

Vice Chancellor for Research, Iran University of Medical Sciences