Differential Plasma MicroRNA Profiles in ED and Normal Erectile Function in Older Males
- Conditions
- Erectile Dysfunction
- Interventions
- Other: Take blood
- Registration Number
- NCT01830049
- Lead Sponsor
- Nanjing Medical University
- Brief Summary
Erectile dysfunction (ED) is strongly associated with aging. With the rapidly expanding aging population and the increase in life expectancy, an increase in the prevalence of ED is expected in the years to come. Currently, the mechanism of ED is not fully understood. MicroRNAs (MiRNA) are endogenous small RNA molecules that control gene expression post-transcriptionally. It has been included in many in vitro physiology and pathophysiology processes, which also involved in the process of ED. This research was designed to investigate the differential plasma MiRNA profiles in ED and normal erectile function in older males. The results might tell us which MiRNA and how did it involved in the process of ED in aging.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 30
- older males with erectile dysfunction
- have some other general diseases, e.g. hypertension, vascular diseases, depression, chronic kidney disease, diabetes.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Group I Take blood Older males with ED Group II Take blood Older males with normal erectile function Gourp III Take blood Young males with normal rectile function
- Primary Outcome Measures
Name Time Method Gene chips 30 days
- Secondary Outcome Measures
Name Time Method RT-PCR 15 days
Trial Locations
- Locations (1)
Nanjing Gulou Hospital affiliated to Nanjing University, Medical School
🇨🇳Nanjing, Jiangsu, China