Comparative Study between the effects of lidocaine infusion, magnesium infusion or dexemedetomidine infusion on haemodynamic responses and postoperati
- Conditions
- Surgerylaparoscopic cholecystectomyAnaesthesia
- Registration Number
- PACTR201606001662120
- Lead Sponsor
- Tanta Univercity hospital anaesthesia department
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 96
96 adult patients, aging (25-65y),(ASA I&II) of both sex presented for laparoscopic cholecystectomy surgery in Tanta University Hospital
¿Cardiovascular instability (elderly & diabetics)
¿Patient with chronic hypertension
¿Sever cardiac deseases. AV block
¿Patients on b-blockers or ca channel blockers
¿History of allergy to local anesthetics.
¿History of allergy to ¿2 agonist drugs .
¿Patient with exaggerated hypertensive response (systolic<180, diastolic <110mmhg)
¿Patients whose operation not completed laparoscopically and converted to open cholecystectomy, surgical time<180 min.
¿Major liver or renal diseases
¿Pregnancy
¿Patients who received opioids or NSAIDS one week prior to surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method is to compare the effects of using intraoperative dexemedetomidine, magnesium or lidocaine infusion on haemodynamic stress response to laryngoscopy , endotracheal intubation, creation of Pneumoperitoneum, and extubation in laparoscopic cholecystectomy.
- Secondary Outcome Measures
Name Time Method