Validation of clinical applicable techniques for end inspiratory lung volume (Vei) measurement.

Completed

• Conditions: pulmonary hyperinflation; too high lung volume; 10038716

• Registration Number: NL-OMON42776
• Lead Sponsor: Intensive Care

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- severe airway obstruction due to obstructive airway diseases ( COPD and asthma)
- controlled mechanical ventilation
- deep sedation
- arterial catheter

Exclusion Criteria

- hypoxemic failure (FiO2 > 70%)
- presence of pneumothorax

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study parameter is the difference in degree of pulmonary<br /><br>hyperinflation, expressed as the volume at end inspiration (Vei) between the<br /><br>gold standard and formula (Vei_measurement versus Vei_formula) and between the<br /><br>gold standard and the ventilator (Vei_measurement versus Vei_ventilator).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Other study parameters are based on clinical outcome of patients, such as<br /><br>incidence of pneumothorax, days on the ventilator and need for vasopressors.</p><br>