Platelet Rich Plasma (PRP) as a Treatment for ACHILLES Tendon Tears

Phase 2

Completed

• Conditions: Achilles Tendon Tear
• Interventions: Biological: placebo; Biological: PRGF

• Registration Number: NCT00731068
• Lead Sponsor: Meir Medical Center

Brief Summary

To review the influence of patient derived PRGF on the healing process of Achilles tendon after a surgical correction of a complete tear.

Detailed Description

Autologous platelet-rich matrices may aid in post surgical patients by promoting and accelerating tissue healing because of the release of growth factors including transforming growth factor (TGF)-beta1 and platelet-derived growth factor (PDGF) from platelet alpha-granules.

Study Timeline

• Study Start: 2007-02
• Study First Submitted: 2008-08-05
• Study First Submitted QC: 2008-08-07
• Study First Posted: 2008-08-08
• Primary Completion: 2009-02
• Study Completion: 2009-03
• Status Verified: 2013-10
• Last Update Submitted: 2013-10-23
• Last Update Posted: 2013-10-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• A complete tear of Achilles tendon
• Age 18-50 years old

Exclusion Criteria

• under 18 year of age
• pregnancy
• physical or mental disabilities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
2	placebo	-
1	PRGF	PRGF

Primary Outcome Measures

Name	Time	Method
improvement of symptoms / disease progress	1 year