NCT00731068已完成2 期
PRP as a Treatment for ACHILLES Tendon Tears - Randomized-Double-Blind-Placebo Control Trail
适应症
干预措施
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 50
- 主要终点
- improvement of symptoms / disease progress
研究概览
简要总结
To review the influence of patient derived PRGF on the healing process of Achilles tendon after a surgical correction of a complete tear.
详细描述
Autologous platelet-rich matrices may aid in post surgical patients by promoting and accelerating tissue healing because of the release of growth factors including transforming growth factor (TGF)-beta1 and platelet-derived growth factor (PDGF) from platelet alpha-granules.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A complete tear of Achilles tendon
- •Age 18-50 years old
排除标准
- •under 18 year of age
- •pregnancy
- •physical or mental disabilities
研究组 & 干预措施
2
Placebo Comparator
干预措施: placebo (Biological)
1
Experimental
PRGF
干预措施: PRGF (Biological)
结局指标
主要结局
improvement of symptoms / disease progress
时间窗: 1 year
次要结局
未报告次要终点
研究者
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