Clinical outcomes of SOI implants in postmenopausal woma

Not Applicable

Conditions: Diseases of the digestive system

Registration Number: KCT0007100

Lead Sponsor: Yonsei University Health System, Dental Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot yet recruiting

Sex: Female

Target Recruitment: 40

Inclusion Criteria

Among the patients who visited Yonsei University College of Dentistry Hospital, among postmenopausal women aged 55 years or older, according to the T-Score, osteoporosis/osteopenia patients group (-3-1) were classified. It is aimed at patients who have missing teeth and need dental implants. (However, at least 3 months have passed since tooth extraction in the edentulous area)

Exclusion Criteria

1. Patients who have previously received head and neck radiation therapy or who have received anti-absorbent drugs (bisphosphonate and denosumab) within the past 1 year for the treatment of osteoporosis
2. Patients with other metabolic bone diseases (Paget's disease, hyperparathyroidism, fibrotic dysplasia, etc.)
3. If a bone graft has been previously performed or extensive bone grafting is required
4. A person who falls under any of the following in the medical device application area
? Those who have had tumors removed in the past
? those with osteomyelitis
? those with blood vessel damage
5. People with uncontrolled diabetes or high blood pressure
6. Heavy smokers (more than 20 cigarettes/day) and alcoholics
7. Patients with severe periodontal disease and tooth decay that may affect implant placement
8. A person who is considered by the research director to have other diseases that may affect bone regeneration and research other than the above

Study & Design

Study Type: Observational Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Marginal bone level measurement: apical photo and CT data (1st surgery, 2nd surgery, follow-up period after prosthetic function)

Secondary Outcome Measures

Name	Time	Method
Resonance frequency analysis :ISQ level ;Measurement of osteoporosis and osseointegration-related values in the surrounding marginal and jaw bones through fractal analysis;Implant survival rate, peri-implantitis evaluation;T-score test through DXA and blood test for bone turnover marker