Efficacy of Carboxytherapy Versus Short-pulsed 1064 nm Nd-YAG Laser Combined With Subcision in Treatment of Cellulite
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 主要终点
- Photonumeric cellulite severity scale
研究概览
简要总结
To evaluate the efficacy of carboxytherapy versus short-pulsed 1064 nm Nd-YAG laser combined with subcision in treatment of cellulite using clinical assessment and ultrasound imaging.
详细描述
Study Design:
Randomized Clinical Trial
Study Methods:
The population of study: Thirty females aged from 18 to 60 years with cellulite Study location: Dermatology outpatient clinic, Faculty of Medicine, Cairo University
Inclusion criteria:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Females between 18 and 60 years
- •Females with cellulite; stage 2 or 3 according to Nurnberger-Muller Scale (Nurnberger and Muller, 1978)
排除标准
- •Subjects that have had liposuction or surgical procedures to remove fat in the past 6 months
- •Personal or family history of keloid formation or scarring
- •Pregnant or lactating females
- •Significant concomitant illness (e.g. renal, cardiac, hepatic, autoimmune conditions)
- •Known history of bleeding tendency or receiving antiplatelet or anticoagulant therapy
- •History of uncontrolled diabetes
- •History of thrombophlebitis within the last 2 years
- •Subjects with active infections
- •Subjects on long term corticosteroid or immunosuppressive therapy
研究组 & 干预措施
Carboxytherapy
Six carboxytherapy sessions with an interval of 2 weeks. Five ccs will be injected at each point with a depth of 7mm. Between each point and the other is 5 cm.
干预措施: Carboxytherapy, short pulsed 1064 Nd Yag laser and subcision (Device)
Short pulsed 1064 nm Nd-YAG laser combined with subcision
Twenty-five joules/cm2, 2.2Hz combined with subcision with an interval of 1 month.
干预措施: Carboxytherapy, short pulsed 1064 Nd Yag laser and subcision (Device)
结局指标
主要结局
Photonumeric cellulite severity scale
时间窗: Change from baseline at 3 months
次要结局
- Ultrasound imaging(Change from baseline at 3 months)