Neurophysiological Approach for the Evaluation of Residual Cognitive Functions in Patients With Severe Alterations of Consciousness

IRCCS Centro Neurolesi "Bonino-Pulejo"1 site in 1 country20 target enrollmentJune 14, 2020

ConditionsConsciousness Disorder Cognitive Impairment

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Consciousness Disorder
Sponsor: IRCCS Centro Neurolesi "Bonino-Pulejo"
Enrollment: 20
Locations: 1
Primary Endpoint: Event-related evoked potentials(ERPs)
Status: Completed
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Identify potential markers of recovery through event-related potentials (ERPs) in the evolution of altered consciousness with potential ability to discriminate between different conditions of altered state of consciousness.

Identify potential markers with prognostic value, in order to identify personalized and specific intensive rehabilitation paths based on the outcome indexes obtained.

Registry

clinicaltrials.gov

Start Date

June 14, 2020

End Date

June 14, 2022

Last Updated

3 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

IRCCS Centro Neurolesi "Bonino-Pulejo"

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Glasgow Coma Scale (GCS) \> 8;
•Level of Cognitive Scale (LCF) = 1-3;
•Signature of the consent from the family member and/or guardian.

Exclusion Criteria

•Failure to sign the consent of the family member and/or legal guardian;
•Patients with cranial anatomical alterations that do not allow the correct assembly of the electrodes, caps, etc.;
•Patients with absence of neurophysiological responses in visual evoked potentials (VEP) and with absence of peripheral waves (I-II wave) to acoustic potentials (PEA).