跳至主要内容
临床试验/NCT04234139
NCT04234139Enrolling By Invitation不适用

Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation

Johns Hopkins University1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2020年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
Enrolling By Invitation
入组人数
300
试验地点
1
主要终点
Number of participants who survived within 1 year post-transplant

研究概览

简要总结

The purpose of this study is to develop a clinical understanding of early liver transplantation (ELT) for patients with severe alcoholic hepatitis (SAH) and identify the public's opinion regarding this practice.

详细描述

The research study is designed to improve the investigators' understanding of early liver transplantation for patients with severe alcoholic hepatitis. The goal of this research is twofold:

  1. Establish a knowledge base necessary for appropriate liver transplant candidate selection by quantifying post-ELT mortality for SAH and compare to outcomes to liver transplantation for other indications
  2. Develop an ethical framework for implementation of these transplants for SAH based on the opinions of healthcare providers and the general public.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Number of participants who survived within 1 year post-transplant

时间窗: 1 years

Post-transplant survival within one year of the surgical procedure.

次要结局

  • Number of participants who self-report or have biochemically measured alcohol recidivism or relapse within 1 year post-transplant(1 years)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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