Improving function of transplanted kidneys

Not Applicable

Completed

• Conditions: Kidney transplantation; Urological and Genital Diseases

• Registration Number: ISRCTN15821205
• Lead Sponsor: Cambridge University Hospitals NHS Foundation trust & University of Cambridge

Brief Summary

2017 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/28115329 protocol 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37231075/ (added 26/05/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-02-10
• Study Completion: 2021-03-19
• Last Update Posted: 5 June 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 338

Inclusion Criteria

1. Patients undergoing DCD kidney transplantation (Maastricht Categories III & IV)
2. DCD donor aged 18 years or over
3. Transplant recipients aged 18 years or over
4. First or second kidney transplant recipients

Exclusion Criteria

1. DCD donors aged under 18 years
2. DCD donors in Maastricht Categories I & II
3. Third and subsequent kidney transplant recipients
4. Multi-organ transplants e.g. simultaneous pancreas-kidney transplantation
5. Dual kidney transplants
6. Paediatric en-bloc kidney transplants
7. Organ preservation by hypothermic machine perfusion

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Delayed graft function rate is determined by the need for dialysis in the first 7 days post-transplant.