ASSESSMENT OF THE EFFECTIVENESS OF IRRIGATION ( WASHING) OF NASAL CAVITY WITH POVIDONE IODINE ( a general antiseptic) IN THE PREVENTION OF VENTILATOR ASSOCIATED PNEUMONIA IN A GENERAL INTENSIVE CARE UNIT
Phase 2
Completed
- Conditions
- Health Condition 1: null- patients receiving mechanical ventilation
- Registration Number
- CTRI/2015/02/005571
- Lead Sponsor
- Post Graduate Institute of medical education and research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
•Age > 18 years
•Newly intubated patients requiring mechanical ventilation for a minimum period of 5 days
Exclusion Criteria
•Patients with pneumonia at the time of hospital admission
•Patients with known allergy to chlorhexidine or povidone iodine
•History of aspiration of oral or gastric contents prior to or during the process of intubation
•Tracheotomised patients
•Patients at risk for chemical meningitis ( nasal bone fracture, cerebrospinal fluid rhinorrhea)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the development of ventilator associated pneumonia as diagnosed using the CDC algorithms <br/ ><br>Timepoint: presence of VAP will be assessed on the 5th day of mechanical ventilation <br/ ><br>
- Secondary Outcome Measures
Name Time Method correlation between the organisms isolated in the oropharyngeal, nasopharyngeal and tracheal culturesTimepoint: 5th day of mechanical ventilation