A Comparative Assessment of Weight Loss and Anti-lipid Effects of Negative Calorie Diet and Low-calorie Diet in Overweight/Obese Middle-aged and Older Women Under Exercise Condition
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 66
- 主要终点
- High-density lipoprotein -cholesterol (HDL-C)
研究概览
简要总结
The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult women with abnormal weight gain.
详细描述
Background: Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method.
Objectives: The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult women with abnormal weight gain.
Material and Methods
Participants included sedentary women (age 45-75 years) with overweight or obesity (n=111). They were randomly divided into two groups including negative calorie diet with exercise, and low-calorie diet with exercise. Of all 111 participants, 90 persons completed the treatment. The weight assessment parameters including change in weight and body composition, blood sample tests were performed pre- and three month post-intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Non-smokers and weight-stable (± 2 kg, for more than one year) with no history of regular exercise in at least three months before the study.
排除标准
- •History of CVD and other disorders such as diabetes, depression, eating disorders, chronic medications, kidney disease, cancer, food allergies or intolerances to items used in meals. Subjects with abnormality in thyroid or Electrocardiograph, any history of anti-obesity medication or weight loss drugs or dietary supplementations for weight control.
结局指标
主要结局
High-density lipoprotein -cholesterol (HDL-C)
时间窗: Baseline
assessed in mg/dl
Triglycerides (TG)
时间窗: Baseline
assessed in mg/dl
Weight
时间窗: Baseline
assessed in kg
Total cholesterol (Total-C)
时间窗: Baseline
assessed in mg/dl
Low-density lipoprotein -cholesterol (LDL-C)
时间窗: Baseline
assessed in mg/dl
次要结局
- High-density lipoprotein -cholesterol (HDL-C)(3-month)
- Weight(3-month)
- Total cholesterol (Total-C)(3-month)
- Low-density lipoprotein -cholesterol (LDL-C)(3-month)
研究者
Mohammadreza Rezaeipour, MD, PhD
Asst. Prof. of sports medicine (sports injury and corrective movement)
University of Sistan and Baluchestan